Supergirl
2015–2021  (CBS, The CW)
Supergirl

O Brother, Where Art Thou?

Supergirl (415) - O Brother, Where Art Thou?

O Brother, Where Art Thou?

Episode #
415
U.S. Air Date
03.17.19
Directed By
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After James is shot Lena turns to her brother, the ailing criminal mastermind Lex Luthor, for help in completing her research — which may be the only way to save both men. Meanwhile Kara joins J’onn on his hunt for Manchester.

U.S. air dates are in MM.DD.YY form.   U.K. air dates are in DD.MM.YY form.
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    JON CRYER GUEST STARS AS ICONIC DC COMICS' VILLAIN LEX LUTHOR

    Secretly furloughed from prison due to failing health, Lex Luthor (guest star Jon Cryer) visits his sister, Lena (Katie McGrath), to seek her help finding a cure. Savvy as ever, Lena is suspicious of Lex's motives but when she's faced with a life and death situation, she must decide how she truly feels about her brother. Meanwhile, Supergirl (Melissa Benoist) and J'onn (David Harewood) face off against Manchester Black (guest star David Ajala). James' sister Kelly (guest star Azie Tesfai) comes to town.

    Tawnia Mckiernan directed the episode written by Derek Simon & Nicki Holcomb (#415).