After Andrea is attacked by an anti-tech extremist on the eve of the launch of her Obsidian Platinum VR system, Supergirl is assigned to be her personal bodyguard. Lena moves forward with her Non Nocere research — using human test subjects inside a prison.

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LENA MOVES FORWARD WITH NON NOCERE

Lex (guest star Jon Cryer) tasks Supergirl (Melissa Benoist) with protecting Andrea (Julie Gonzalo) from an anti-tech extremist, but his nefarious purpose goes beyond merely keeping Andrea alive. Meanwhile, Lena (Katie McGrath) moves forward with Non Nocere, with Lex's help.

Gregory Smith directed the episode with story by Lindsay Sturman and teleplay by Emilio Ortega Aldrich & Chandler Smidt (#514).