Astronaut John Crichton is sent through a wormhole to a distant part of the universe, where he joins a crew of escaped prisoners on board a living ship -- pursued by a renegade Peacekeeper commander out for vengeance.
New friends join the crew, and Crichton must flee from the cunning Scorpius -- a Scarran-Sebacean hybrid bent on obtaining advanced wormhole technology locked away in John's brain by an advanced alien species.
Old friends say goodbye and a new face joins Moya's crew, as John Crichton and his friends endure the "season of death." The lost astronaut searches for the key to wormhole travel -- before the enemy gets there first.
Moya's crew finds a dangerous new enemy and the most unlikely ally as they flee the Peacekeepers and Scarrans into a terrifying part of the universe. Two more oddballs join the ship, and John and Aeryn struggle with their future.
Moya and her crew are thrust into the middle of an inevitable war between the Scarrans and the Peacekeepers, and seek help from a race of beings with a natural ability to bring about peace -- so that John Crichton does not have to resort to using his knowledge of wormhole weapons.