After alien survivors of a galaxy-wide war arrive on Earth, humans and aliens build a new society on the ruins of St. Louis in the hopes of living peaceably together.
The town of Defiance comes under Earth Republic control, as Nolan searches the badlands for his daughter and the Tarr family seeks to maintain its criminal empire.
Following the collapse of the mines and an impending military siege, the future of Defiance is made even more uncertain by the arrival of a mysterious and nearly extinct species called the Omec -- warriors marked by the decades of subjugation they once imposed upon the galaxy.
