Helix is an intense thriller about a team of scientists from the Centers for Disease Control who travel to the high-tech research facility, Arctic BioSystems, to investigate a possible disease outbreak, only to find themselves pulled into a terrifying life-and-death struggle that may hold the key to mankind's salvation or total annihilation. However, the lethal threat is just the tip of the iceberg, and as the virus evolves, the chilling truth begins to unravel.

Billy Campbell (Killing Lincoln, The Killing) stars as Dr. Alan Farragut, leader of the Centers for Disease Control outbreak field team called upon to investigate and control a potential outbreak. Hiroyuki Sanada (The Wolverine, 47 Ronin) also stars as Dr. Hiroshi Hatake, director of Arctic BioSystems and its mysterious viral research program.
Helix also stars Kyra Zagorsky (Supernatural) as Dr. Julia Walker; Mark Ghanimé (Emily Owens, M.D.) as Major Sergio Balleseros; Jordan Hayes (House at the End of the Street) as Dr. Sarah Jordan; Meegwun Fairbrother as Daniel Aerov; Catherine Lemieux (White House Down) as Dr. Doreen Boyle, and Neil Napier (Riddick) as Dr. Peter Farragut.

Ronald D. Moore (Battlestar Galactica, Outlander), Steven Maeda (Lost, The X-Files) who is also showrunner, and Lynda Obst (Contact, Sleepless in Seattle) are Executive Producers. The 13-episode series is produced by Tall Ship Productions, Kaji Productions and Lynda Obst Productions in association with Sony Pictures Television. Prolific director and producer Jeffrey Reiner (Friday Night Lights) directed the premiere episode, which was written by creator and co-executive producer, Cameron Porsandeh.