After discovering that the Cabal has turned Ashley into a super-powered killer who is targeting the Sanctuary network, Magnus and her team scramble to find a way to counteract the transformation — as the enemy sends a team to attack the U.K. Sanctuary directly.
While the Sanctuary deals with a massive intake of abnormals from Tokyo and London, Magnus struggles with the possibility that her daughter may be dead. Kate helps the team track a one-of-a-kind creature she accidentally set loose.
The team's efforts are thwarted by an ordinary man playing superhero in the city, thanks to a suit that gives him special powers. A crime boss uses Kate's brother to convince her to work for him, and the team hunts a rapidly-evolving insectoid creature.
After awakening in a ruined Sanctuary amidst a decimated city, Magnus finds that she has stepped into a dystopian version of reality where her alternate version is dead ... and Will is engaged in a brutal fight against a horde of savage creatures.
While transporting a rare sea creature captured in the Gulf of Mexico Magnus and Will crash land inside a decomissioned oil rig, leaving them trapped with little hope of rescue.
An old friend of Magnus finds himself on the run from an Abnormal mob after a delivery to the Sanctuary is interrupted — and Kate is caught in the crossfire.
The disappearances of a group of teenagers point Will and Magnus to a rehab facility in Mexico, where they find that Nikola Tesla may have inadvertantly recreated a race of vampires.
After he rescues a group of empaths off a sinking ship, John Druitt becomes the prime suspect when one of the women turns up murdered inside the Sanctuary ... indicating that the bloodlust of Jack the Ripper may have finally gotten the better of him.
When the team travels to Mumbai, India, to investigate a murder believed to be linked to the Cult of Kali, Will is infected by a mysterious illness and disappears.
Will finds himself psychically connected with Kali, one of the most powerful Abnormals on Earth, who is also the target of a wealthy man seeking to be connected with her, as well.
