Sisko hopes to find a way to reconnect with the Prophets, leading him to a secret about his father's past -- and making him the target of a new Bajoran cult. Kira finds her new working relationship with a Romulan Senator too good to be true.
Ben goes in search of the Orb of the Emissary, believing it will restore the wormhole and reveal the truth about his mother. Kira initiates a blockade to try and force the Romulans to remove weapons from a Bajoran moon, while Worf leads a mission to honor his fallen wife.
Weyoun defects from the Dominion, calling on Odo to help him escape and pledging his loyalty to him. Chief O'Brien is in a predicament when he trusts Nog to secure an important component.
An aging Klingon legend seeks Worf's help in finding glory in battle once again, leading to a dangerous confrontation with the Dominion. Worf learns that General Martok has a personal grudge against the hero.
Sisko and a team from DS9 arrive on a Federation planet under siege by the Jem'Hader, and must take command of the bloody conflict to help a team of battle-weary soldiers hold the outpost.
Nog returns to the station after months of therapy following the replacement of his leg, and moves into Vic Fontaine's holosuite program when he has trouble readjusting to his life and relationships.
Ezri is forced to return home after Chief O'Brien goes missing, not knowing that the family business has become involved with the deadly Orion Syndicate.
Quark and Rom visit the treacherous alternate universe when Grand Nagus Zek becomes a prisoner of the Alliance, who demand a cloaking device in exchange for his release.
The murder of a promising young officer sends Ezri on a quest to find his killer -- for which she seeks help from Joran Dax, a psychotic murderer who was once host to her symbiant.
A solo changeling who is not one of the Founders visits the station, seeking out Odo as the first one of his kind he has ever encountered -- and encouraging him to give up his life with humanoids and join him in exploring the galaxy.
When Vic Fontaine's holosuite lounge is taken over by mobsters, DS9's senior staff hatches a plot to rob the casino and drive Vic's nemesis out of town.
Ezri steals a runabout to go in search of Worf when his ship is destroyed in combat, only to be stranded with him on an uninhabited planet. Captain Sisko and Kasidy Yates make plans for their future, while Dukat seeks an unusual favor from Damar.
Sisko must decide whether or not to go through with his wedding when the Prophets warn him not to. Dukat poses as a Bajoran farmer to gain the trust of Kai Winn, while Worf and Dax sort through their new relationship while prisoners of the Breen.
Ezri and Worf attempt to escape the Dominion, who have made a powerful new ally in the war with the Federation. Winn must make an important decision when her faith is challenged.
The Breen strike at the heart of the Federation, and Captain Sisko and crew join a battle to retake a key star system. Winn seeks answers in the dark texts of the Pah Wraiths, only to discover the truth about her new companion.
Starfleet sends Kira to teach guerrilla tactics to Damar's new Cardassian resistance movement. Bashir uncovers startling news about Odo, and the Klingon Chancellor announces a questionable strategy.
Kira, Odo, and Gerak join the Cardassian resistance in a daring plan to steal the new Breen weapon. Klingon Chancellor Gowron's faulty war tactics force Worf to move against him, while Bashir and O'Brien look for a way to lure Section 31 into a trap.
Dr. Bashir and Chief O'Brien lure Sloan, the enigmatic agent of Section 31, into a trap to try and extract the cure for Odo's disease from his mind -- before Odo's time runs out.
The Cardassian resistance movement hangs by a thread when the Dominion sets a trap for Damar. The Grand Nagus announces his intention to retire and name Quark as his successor.
The Alpha Quadrant alliance launches its final assault on the Dominion stronghold, a battle that will decide the war. The Cardassian people rise up against the Dominion, while Kai Winn and Dukat attempt to release the Pah Wraiths.
The Dominion War finally comes to an end, but at a great cost to Cardassia. Odo offers the Founders the cure for the disease that threatens to destroy them, and the crew of Deep Space Nine prepares to go their separate ways.