Archer must work with Silik to rescue two of his crew from Vosk, and prevent the alien insurgents from returning to their own time in order to restore the timeline.
The crew returns home to find that the world they have saved is no longer the same. Archer confronts his actions from the past year, while T'Pol and Trip arrive on Vulcan only to discover her fiancé waiting for her.
Archer enlists the help of criminal geneticist Arik Soong when a group of enhanced humans hijack a Klingon ship. But when Orions capture nine crew members, they must first rescue them from a slave market.
Soong and his Augment "children" attack a research station where hundreds of genetically-enhanced embryos are being stored, intent on creating an entire race of the supermen.
Malik seizes command of the Augments to attempt to wipe out a Klingon colony and spark an interstellar war, forcing Dr. Soong to reconsider his plans for the genetically engineered race.
Archer and T'Pol come face to face with the Syrrannites, only to learn that the essence of the ancient Vulcan philosopher Surak has been placed in the captain's mind.
While Enterprise attempts to stop an interstellar war between Vulcan and Andoria, Archer and the Syrrannites must bring the true teachings of Surak to the Vulcan capital.
Enterprise plays host to Emory Erickson, the inventor of the transporter, for a risky experiment intended to lead to transportation through subspace -- which he is using to conceal his true mission.
Hoshi and Trip are quarantined when they return from an away mission with an alien virus, not aware of the fact that two non-corporeal aliens have possessed the bodies of the crew to study how humans respond to the crisis.
Enterprise's mission to deliver a Tellarite ambassador to peace talks with the Andorians is interrupted when the ship answers a distress call -- and finds an Andorian warship that Commander Shran claims was attacked by their new "allies."
Archer's only hope of unifying the Andorians, Tellarites, and Vulcans to stop a ship threatening to destabilize the region is to face Shran in hand-to-hand combat ... to the death. Malcolm and Trip are stranded aboard the Romulan-controlled marauder.
Captain Archer travels to Shran's icy homeworld of Andoria to locate a subspecies called the Aenar, believing they are connected to the chameleon marauder that is destroying ships and destabilizing the region.
Phlox is kidnapped and delivered to the Klingons, who need his help to stop a secret plague. Trip transfers to the Columbia, and Reed acts in secret to mislead Captain Archer.
The crew of Enterprise must deal with sabotage before they can rescue Dr. Phlox, who is challenged to cure the Klingon plague before the Empire eradicates the research colony.
Archer strikes a deal with an Orion trader, and finds himself in possession of three Orion Slave Girls -- whose presence has seductive effects on the men of the crew.
In a mirror universe, Commander Archer mutinies against Enterprise Captain Forrest in a bold move to capture an advanced ship rumored to have come from the future, and now in Tholian space.
In the mirror universe, Archer seizes command of the Defiant with the intention of taking control of the entire Empire by force. But friends and foes alike plot schemes of their own.
The Enterprise crew visits Earth for a peace conference and runs afoul of Terra Prime, a xenophobic faction in possession of a Vulcan-human hybrid child. Travis is reunited with an old flame.
After a human isolationist group seizes control of dangerous technology and demands all aliens leave Earth, the Enterprise crew must infiltrate the facility to stop them.
As the crew reach their tenth year of voyages on Enterprise the ship returns home for the signing of the Federation charter, only to be sidetracked when an old friend asks for their help.
